Chronic actinic keratopathy

Topic Completed: 1 October 2013

Minor changes: 22 December 2020

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PubMed Search: Chronic actinic keratopathy

Nat Pernick, M.D.
Page views in 2020: 200
Page views in 2021 to date: 240
Cite this page: Pernick N. Chronic actinic keratopathy. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyecorneachronicactinickeratopathy.html. Accessed December 6th, 2021.
Definition / general
  • Also called climatic droplet keratopathy or spheroidal degeneration
  • Initially involves periphery of cornea, increases in severity and incidence with age
  • Associated with long term exposure to excessive ultraviolet light
Microscopic (histologic) description
  • Amorphous globules of protein accumulate in superficial stroma of interpalpebral portion of cornea
Differential diagnosis
  • Other disorders produce similar globules
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