Other tumors

Seborrheic keratosis

Topic Completed: 1 February 2014

Minor changes: 29 December 2020

Copyright: 2004-2021, PathologyOutlines.com, Inc.

PubMed Search: Seborrheic keratosis [title] eyelid

Nat Pernick, M.D.
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Page views in 2021 to date: 3,387
Cite this page: Pernick N. Seborrheic keratosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyeeyelidseborrheickeratosis.html. Accessed December 6th, 2021.
Gross description
  • Elevated irregular lesions, often crusty or greasy appearing
  • Often pigmented
Microscopic (histologic) description
  • Acanthosis with marked hyperkeratosis and keratin filled cysts
  • Also increased pigmentation in basal layer
  • No atypia
Microscopic (histologic) images

AFIP images
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Plaque-like lesion with cords of basaloid
cells and numerous horn cysts

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Irritated seborrheic keratosis (inverted follicular
keratosis) has acanthotic epithelium with massive
hyperkeratosis forming a cutaneous horn; numerous
squamous eddies within acanthotic epithelium

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