Lacrimal duct / gland

Pleomorphic adenoma-lacrimal duct

Last author update: 1 February 2014
Last staff update: 27 May 2022

Copyright: 2004-2024, PathologyOutlines.com, Inc.

PubMed Search: Pleomorphic adenoma lacrimal gland

Nat Pernick, M.D.
Page views in 2023: 1,790
Page views in 2024 to date: 251
Cite this page: Pernick N. Pleomorphic adenoma-lacrimal duct. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyelacrimalpleomorphicadenoma.html. Accessed February 26th, 2024.
Definition / general
  • 50 - 60% of lacrimal gland tumors
  • Resemble salivary gland tumors of same type
  • Excisional biopsy with negative margins to prevent recurrence and implantation within the orbit
Microscopic (histologic) description
  • Usually encapsulated, composed of benign epithelial and myxoid mesenchymal elements
  • Often prominent component of S100+ hyaline cells (presumed myoepithelial origin) with diffuse eosinophilic staining
  • May have squamous metaplasia, bone, cartilage or fat
Microscopic (histologic) images

AFIP images
Missing Image

Well circumscribed
lacrimal gland

Missing Image

Islands of epithelial cells, myxoid stroma and cysts

Missing Image

Double layer of epithelial cells within a myxoid stroma

Missing Image

Chondroid differentiation

With carcinoma
Missing Image

Large round nodule of pleomorphic adenoma

Missing Image

Benign ducts within
myxoid stroma;

Missing Image

With adenoid cystic carcinoma

Back to top
Image 01 Image 02