Eye
Conjunctiva
Melanocytic tumors
Inflammatory juvenile conjunctival nevus
Author: Deepali Jain, M.D.
Last author update: 1 October 2014
Last staff update: 4 March 2021
Copyright: 2004-2023, PathologyOutlines.com, Inc.
PubMed Search: Inflammatory juvenile conjunctival nevus
Related Topics: Nevi
Table of Contents
Definition / general | Treatment | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosis | Additional referencesCite this page: Jain D. Inflammatory juvenile conjunctival nevus. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyenevijuvenile.html. Accessed September 28th, 2023.
Definition / general
- Benign, inflammatory juxtalimbal lesion characterized by marked eosinophils
- Children and teenagers
- May grow rapidly and cause congestion, and clinically resemble melanoma
- Associated with systemic allergies and bilateral papillary conjunctivitis (Br J Ophthalmol 2002;86:28)
Treatment
- Excision and close follow up
Microscopic (histologic) description
- Confluent growth pattern and a lack of maturation
- Epithelial cysts and solid islands composed of benign nevus cells
- Also prominent eosinophils and mast cells (some degranulated)
- Often lymphocytes (52%) and lymphoid follicles (Invest Ophthalmol Vis Sci 2002;43:1850) and plasma cells
- MUC5AC in enlarging cysts (Jpn J Ophthalmol 2012;56:107)
Microscopic (histologic) images
Images hosted on other servers:
Various images
Nerve growth factor and eosinophils
IHC for NGF and eosinophils
Differential diagnosis
Additional references
