Eye

Orbit & optic nerve

Coloboma



Topic Completed: 1 February 2014

Minor changes: 22 December 2020

Copyright: 2004-2021, PathologyOutlines.com, Inc.

PubMed Search: coloboma [title] optic nerve

Nat Pernick, M.D.
Page views in 2020: 250
Page views in 2021 to date: 454
Cite this page: Pernick N. Coloboma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyeorbitcoloboma.html. Accessed December 6th, 2021.
Definition / general
  • Unilateral abnormality of optic nerve head, of congenital origin
  • Complete coloboma may form large hole or posterior protrusion near optic nerve
Microscopic (histologic) description
  • Large defect with mostly bare sclera, lined by fibrous or glial tissue
  • May involve retina and choroid along its edges
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