Eye
Orbit & optic nerve
Idiopathic sclerosing inflammation
Author: Nat Pernick, M.D.
Last author update: 1 February 2014
Last staff update: 24 December 2020
Copyright: 2004-2023, PathologyOutlines.com, Inc.
PubMed Search: Idiopathic sclerosing inflammation [title] orbit
Cite this page: Pernick N. Idiopathic sclerosing inflammation. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyeorbitidiopathicsclerosing.html. Accessed September 28th, 2023.
Definition / general
- Insidious, chronic and progressive fibrosing process
- Damages orbital structures by entrapment and mass effect
- May have cell mediated pathogenesis, similar to retroperitoneal fibrosis (Mod Pathol 1993;6:581)
Microscopic (histologic) description
- Desmoplasia, sparse lymphocytes (usually T cells), histiocytes, plasma cells, neutrophils, eosinophils
