Cite this page: Pernick N. Idiopathic sclerosing inflammation. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyeorbitidiopathicsclerosing.html. Accessed January 22nd, 2021.
Definition / general
- Insidious, chronic and progressive fibrosing process
- Damages orbital structures by entrapment and mass effect
- May have cell mediated pathogenesis, similar to retroperitoneal fibrosis (Mod Pathol 1993;6:581)
Microscopic (histologic) description
- Desmoplasia, sparse lymphocytes (usually T cells), histiocytes, plasma cells, neutrophils, eosinophils