Orbit & optic nerve


Topic Completed: 1 February 2014

Minor changes: 29 December 2020

Copyright: 2004-2021, PathologyOutlines.com, Inc.

PubMed Search: Meningioma [title] orbit

Nat Pernick, M.D.
Page views in 2020: 489
Page views in 2021 to date: 784
Cite this page: Pernick N. Meningioma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyeorbitmeningioma.html. Accessed December 3rd, 2021.
Definition / general
  • Arise from meninges of optic nerve or extension of cranial meninges
  • Less common than intracranial tumor
  • Associated with hearing loss, optic atrophy and exophthalmos
  • Also papilledema if arises near inner sphenoidal ridge
Radiology images

AFIP images
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MR - large tumor
of orbital apex
causing proptosis

Clinical images

AFIP images
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Tumor arising adjacent to sphenoid
wing has invaded superior
lateral orbit causing downward
displacement and proptosis

Microscopic (histologic) description
  • Meningothelial pattern of whorled spindle cells, psammoma bodies
Microscopic (histologic) images

AFIP images
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Tumor growth within dura
has markedly compressed
the optic nerve

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Tumor of superior lateral
orbit, and unrelated to
meninges of optic nerve

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Invasion of sphenoid bone

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Islands of meningothelial
cells infiltrate
extraocular muscle

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Meningothelial cells
arranged in small nests
with a whorled pattern

Differential diagnosis
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