Eye
Conjunctiva
Epithelial tumors
Steatocystoma simplex
Author: Deepali Jain, M.D.
Last author update: 1 July 2013
Last staff update: 10 June 2022
Copyright: 2004-2024, PathologyOutlines.com, Inc.
PubMed Search: Steatocystoma simplex eye
Table of Contents
Definition / general | Etiology | Clinical features | Case reports | Treatment | Clinical images | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosis | Additional referencesCite this page: Jain D. Steatocystoma simplex. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyesteatocytomasimplex.html. Accessed April 18th, 2024.
Definition / general
- Rare benign adnexal tumor, usually in caruncle
- Steatocystoma simplex if solitary; steatocystoma multiplex if multiple cysts
- Due to nevoid malformation of pilosebaceous duct junction
Etiology
- Autosomal dominant trait in multiplex
Clinical features
- Typically affects individuals younger than 30 years; contains yellow sebum associated with hairs
Case reports
- 26 year old woman with tumor of caruncle (Br J Ophthalmol 2003;87:240)
- 42 year old man with tumor of caruncle (Can J Ophthalmol 2006;41:83)
- 57 year old man and 85 year old man with intratarsal keratinous cysts of the meibomian gland (Am J Dermatopathol 2011;33:624)
Treatment
- Simple excision with removal of cyst wall intact
Clinical images
Images hosted on other servers:
Pale yellow lesion
Gross description
- Flesh colored or yellowish, well circumscribed, soft, mobile, and non-tender
- On incision contains oily sebum
Microscopic (histologic) description
- Cystic space lined by nonkeratinizing squamous epithelium with an eosinophilic cuticle and sebaceous lobules within the cyst wall, but no granular layer
Microscopic (histologic) images
Images hosted on other servers:
Cyst lined by
squamous epithelium
with sebaceous glands
in cyst wall
Differential diagnosis
- Keratinous cyst:
- Older adults, no sebaceous glands in or adjoining wall
Additional references
