Uvea (iris, choroid and ciliary body), limbus and sclera


Topic Completed: 1 February 2014

Minor changes: 22 December 2020

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PubMed Search: choroid [title] eye review[ptyp]

Nat Pernick, M.D.
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Cite this page: Pernick N. Choroid. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyeuveachoroidgeneral.html. Accessed December 6th, 2021.
Definition / general
  • Middle layer of globe between outer sclera and inner retina
  • Highly vascular but no lymphatics
  • Extends from ciliary body to optic nerve
  • Inner aspect is adherent to retinal pigment epithelium; outer surface is loosely attached to overlying sclera
  • Stroma contains abundant pigmented melanocytes
  • Bruch membrane: separates choroid from overlying retinal pigment epithelium, is 2 - 4 microns thick, has 5 distinct layers (basal lamina of overlying retinal pigment epithelium, collagenous layer, elastic fiber rich layer, collagenous layer and basal lamina of endothelial cells of choriocapillaris), thickens with age, has focal excrescences known as drusen
  • Choriocapillaris: in innermost choroidal stroma adjacent to Bruch membrane, connects with arterial and venous channels from vessels in outer choroidal stroma to nourish outer retinal layers

Images hosted on other servers:
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Choroid and iris

Microscopic (histologic) images

AFIP images
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Vascularized pigmented
stroma between Bruch
membrane (middle)
and sclera (below)

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Uveal tissue extends
into sclera within
sclera canals around
a long ciliary vessel

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