Uvea (iris, choroid and ciliary body), limbus and sclera


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PubMed Search: Eye Uvea Uveitis[title] AND (free full text[sb] AND Humans[Mesh])

Nat Pernick, M.D.
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Table of Contents
Definition / general
Cite this page: Pernick N. Uveitis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyeuveauveitis.html. Accessed October 4th, 2023.
Definition / general
    Anterior uveitis (iridocyclitis):
  • Diffuse infiltration by plasma cells, occasionally nodular lymphocytic infiltrates
  • Associated with obliteration of anterior chamber and adherence of iris to cornea
  • May be seen in juvenile rheumatoid arthritis

  • Posterior uveitis (choroiditis, chorioretinitis):
  • Diffuse, focal or scattered chronic inflammatory infiltrate, often involving retina
  • May form cyclitic membrane that contracts, leading to detachment of retina and ciliary body
  • Not painful, so enucleation often not necessary
  • Enucleation if recurrence leads to adhesions between iris and cornea (anterior synechiae) or iris and anterior surface of lens (posterior synechiae) causing secondary glaucoma
  • Cause usually cannot be determined; known causes are herpes zoster, Behcet's disease (obliterative vasculitis of retinal vessels), Pneumocystis carinii

  • Granulomatous uveitis:
  • May be due to sarcoidosis
  • Also tuberculosis, leprosy, syphilis, tularemia, CMV, varicella zoster virus, fungi and parasites
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