Fallopian tubes & broad ligament

Fallopian tube tumor-like lesions

Tubal hyperplasia

Last author update: 1 April 2013
Last staff update: 16 June 2022

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PubMed Search: Epithelial hyperplasia

Nicole D. Riddle, M.D.
Jamie Shutter, M.D.
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Cite this page: Riddle N, Shutter J. Tubal hyperplasia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/fallopiantubesepithelialhyper.html. Accessed March 22nd, 2023.
Definition / general
  • Hyperplasia of tubal epithelium, variable atypia
  • Also known as pseudocarcinomatous hyperplasia
Clinical features
  • Often incidental finding
Gross description
  • No specific gross findings
Microscopic (histologic) description
  • Papillary, gland-like or cribriform patterns, lined by epithelial cells with mild to moderate nuclear pleomorphism, loss of polarity, stratification, crowding, hyperchromasia and scattered mitotic figures; no invasion
  • May be associated with severe inflammation and scarring mimicking adenocarcinoma
Microscopic (histologic) images

AFIP images
Hyperplasia of tubal epithelium of unknown cause

Hyperplasia of tubal epithelium of unknown cause

Clear cell hyperplasia of pregnancy

Clear cell hyperplasia of pregnancy

Differential diagnosis
  • Carcinoma: typically grossly evident, older age, solid epithelial proliferation, brisk mitotic activity, severe atypia, possible invasion
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