Fallopian tubes & broad ligament
Fallopian tube tumor-like lesions
Tubal hyperplasia
Authors: Nicole D. Riddle, M.D., Jamie Shutter, M.D.
Last author update: 1 April 2013
Last staff update: 16 June 2022
Copyright: 2002-2023, PathologyOutlines.com, Inc.
PubMed Search: Epithelial hyperplasia
Table of Contents
Definition / general | Terminology | Epidemiology | Clinical features | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosisCite this page: Riddle N, Shutter J. Tubal hyperplasia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/fallopiantubesepithelialhyper.html. Accessed March 22nd, 2023.
Definition / general
- Hyperplasia of tubal epithelium, variable atypia
Terminology
- Also known as pseudocarcinomatous hyperplasia
Epidemiology
- Typically present in women with estrogen producing ovarian tumors (Int J Gynecol Pathol 1989;8:214)
- May also be associated with salpingitis and PID (Am J Surg Pathol 1994;18:1125)
Clinical features
- Often incidental finding
Gross description
- No specific gross findings
Microscopic (histologic) description
- Papillary, gland-like or cribriform patterns, lined by epithelial cells with mild to moderate nuclear pleomorphism, loss of polarity, stratification, crowding, hyperchromasia and scattered mitotic figures; no invasion
- May be associated with severe inflammation and scarring mimicking adenocarcinoma
Microscopic (histologic) images
AFIP images
Hyperplasia of tubal epithelium of unknown cause
Clear cell hyperplasia of pregnancy
Differential diagnosis
- Carcinoma: typically grossly evident, older age, solid epithelial proliferation, brisk mitotic activity, severe atypia, possible invasion
