Fallopian tubes & broad ligament

General

WHO classification


Editorial Board Member: Ricardo R. Lastra, M.D.
Deputy Editor-in-Chief: Jennifer A. Bennett, M.D.
Gulisa Turashvili, M.D., Ph.D.

Last author update: 2 September 2022
Last staff update: 2 September 2022

Copyright: 2022, PathologyOutlines.com, Inc.

PubMed Search: WHO classification of fallopian tube

Gulisa Turashvili, M.D., Ph.D.
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Cite this page: Turashvili G. WHO classification. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/fallopianwhoclassification.html. Accessed December 3rd, 2022.
Definition / general
  • WHO classification of tumors of the female genital tract
  • Currently on 5th edition, published in 2020
Major updates
  • No major updates, mostly refined definitions
  • Most high grade serous carcinomas of the ovary arise at the fimbriated end of the fallopian tube from a precursor lesion known as serous tubal intraepithelial carcinoma (STIC) (Pathology 2015;47:423, Mod Pathol 2015;28:1101)
  • Undifferentiated carcinoma of the fallopian tube is no longer a separate category
WHO (2020) - fallopian tube


    Mixed epithelial and mesenchymal tumors
  • Adenosarcoma8933/3

    Germ cell tumors
  • Mature teratoma, NOS9080/0
  • Immature teratoma, NOS9080/3
WHO (2020) - broad ligament and other uterine ligaments


    Tumor-like lesions
  • Adrenocortical remnants
Microscopic (histologic) images

Contributed by Gulisa Turashvili, M.D., Ph.D.

STIC associated with invasion

Endometrioid adenocarcinoma

Salpingitis isthmica nodosa

Board review style question #1
What is a precursor lesion of most high grade serous carcinomas?

  1. Low grade serous carcinoma
  2. Ovarian cortical inclusion cysts
  3. Paratubal cyst
  4. Serous borderline tumor
  5. Serous tubal intraepithelial carcinoma (STIC)
Board review style answer #1
E. Serous tubal intraepithelial carcinoma (STIC)

Comment Here

Reference: Fallopian tubes & broad ligament - WHO classification
Board review style question #2

What is the most likely diagnosis for this salpingectomy specimen?

  1. Focal tubal hyperplasia
  2. High grade serous carcinoma
  3. High grade serous carcinoma and serous tubal intraepithelial carcinoma (STIC)
  4. Low grade serous carcinoma
  5. Serous tubal intraepithelial carcinoma (STIC)
Board review style answer #2
C. High grade serous carcinoma and serous tubal intraepithelial carcinoma (STIC)

Comment Here

Reference: Fallopian tubes & broad ligament - WHO classification
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