Gallbladder & extrahepatic bile ducts
Gallbladder malignant
Carcinoma in situ

Topic Completed: 1 September 2012

Minor changes: 13 November 2019

Copyright: 2003-2019,, Inc.

PubMed Search: Carcinoma in situ[TIAB] gallbladder

Hanni Gulwani, M.B.B.S.
Page views in 2019: 1,182
Page views in 2020 to date: 717
Cite this page: Gulwani H. Carcinoma in situ. website. Accessed August 6th, 2020.
Definition / general
Diagrams / tables

Images hosted on other servers:

Comparison of CIS with invasive carcinoma

Microscopic (histologic) description
  • May extend into Rokitansky-Aschoff sinuses resembling invasive carcinoma but is connected to surface epithelium (Am J Surg Pathol 2004;28:621)
  • Mixture of benign and neoplastic epithelium
  • Has inspissated bile in long dilated spaces
  • Desmoplasia but no invasion into smooth muscle bundles, no perineurial invasion
  • May arise in adenomyomatous hyperplasia
Microscopic (histologic) images

Images hosted on other servers:

Various images

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