Extrahepatic bile ducts
Dysplasia of extrahepatic bile ducts

Topic Completed: 1 September 2012

Minor changes: 13 September 2019

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PubMed Search: Dysplasia[TI] extrahepatic bile ducts

Hanni Gulwani, M.B.B.S.
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Cite this page: Gulwani H. Dysplasia of extrahepatic bile ducts. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/gallbladderdysplasiaofextrahepatic.html. Accessed June 1st, 2020.
Definition / general
  • Spectrum from hyperplasia to high grade dysplasia to invasive adenocarcinoma exists, similar to intraductal papillary mucinous neoplasms
  • High grade dysplasia at cystic duct margin is rare without invasive carcinoma (HPB (Oxford) 2011;13:865)
  • Almost universally abnormally short telomeres (Mod Pathol 2006;19:772)
Microscopic (histologic) description
  • May have prominent subnuclear vacuoles
Microscopic (histologic) images

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High grade dysplasia of cystic duct margin

Figures 3 and 4

Positive stains
Negative stains
Differential diagnosis
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