Bone & joints
Other nonneoplastic
Synovial lipomatosis
Author: Vijay Shankar, M.D.
Last author update: 1 June 2013
Last staff update: 26 January 2022
Copyright: 2002-2023, PathologyOutlines.com, Inc.
PubMed Search: Synovial lipomatosis
Table of Contents
Definition / general | Clinical features | Treatment | Gross description | Microscopic (histologic) description | Microscopic (histologic) imagesCite this page: Shankar V. Synovial lipomatosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/jointssynoviallipomatosis.html. Accessed May 29th, 2023.
Definition / general
- Also called Hoffa disease, villous lipomatous proliferation of synovium, lipoma arborescens
- Pseudotumor of synovium with distinct histomorphology, possibly due to inappropriate fat deposition and degenerative articular diseases of joints (J Lab Physicians 2011;3:84)
Clinical features
- Rare; usually knee but may occur in any joint
- Unknown etiology
- Males commonly affected with pain and swelling of joint
Treatment
- Arthroscopy and excision
Gross description
- Enlargement of infrapatellar fat pad with pain in anterior compartment of knee; synovium is papillary, yellow and fatty
Microscopic (histologic) description
- Synovial hyperplasia with unremarkable fat extending to synovial lining; occasional chronic inflammatory infiltrate
Microscopic (histologic) images
Images hosted on other servers:
Villi-like structures
Papillary architecture
Mature adipocytes
Focal hyperplasia
Few mature lipocytes
