Kidney nontumor / medical renal
Infection
Adenovirus
Author: Nikhil Sangle, M.D.
Last author update: 27 November 2018
Last staff update: 19 February 2021
Copyright: 2003-2024, PathologyOutlines.com, Inc.
PubMed Search: Adenovirus [title] kidney pathology
Table of Contents
Definition / general | Microscopic (histologic) description | Microscopic (histologic) images | Electron microscopy descriptionCite this page: Sangle N. Adenovirus. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/kidneyadenovirus.html. Accessed May 6th, 2024.
Definition / general
- May cause necrotizing tubulointerstitial nephritis with hemorrhagic cystitis or prostate involvement
- Associated with bone marrow or other transplant recipients (Transpl Infect Dis 2011;13:174, Am J Kidney Dis 2012;59:886, Am J Transplant 2011;11:1308) and chemotherapy
- Adenovirus activation after immunosuppression can lead to systemic infection and may trigger rejection or early graft loss (Transpl Infect Dis 2011;13:168)
- Adenovirus is also used as a vector for gene therapy (Transpl Immunol 2011;25:34)
Microscopic (histologic) description
- Hemorrhage and necrosis
- Tubulitis with intranuclear inclusion bodies; either smudge cells, Cowdry A intranuclear inclusions or full type intranuclear containing cells (Hum Pathol 1991;22:1225)
Microscopic (histologic) images
Images hosted on other servers:
Various images
Adenovirus immunoperoxidase stain
Electron microscopy description
- Intranuclear crystalline arrays of 75 - 80 nm viral particles
