Kidney nontumor



Renal sinus lipomatosis / renal replacement lipomatosis

Topic Completed: 1 February 2016

Minor changes: 7 June 2021

Copyright: 2003-2021,, Inc.

PubMed Search: Renal sinus lipomatosis [title]

Pallav Gupta, M.D.
Page views in 2021 to date: 578
Cite this page: Gupta P. Renal sinus lipomatosis / renal replacement lipomatosis. website. Accessed December 8th, 2021.
Definition / general
  • Renal sinus lipomatosis is a benign proliferation of fat that occurs with advanced age, obesity and exposure to steroids
  • Renal sinus and perirenal fat proliferation are often caused by renal calculi
  • Most renal parenchyma is replaced by fat, and the kidney is usually small, atrophic and nonfunctioning
  • Associated with xanthogranulomatous pyelonephritis (Rev Assoc Med Bras 2011;57:262)

  • Renal replacement lipomatosis is characterized by complete replacement of the kidney by adipose tissue, with varying degrees of fibrosis
  • It is considered a severe form of renal sinus lipomatosis (Radiographics 2004;24:S117)
Essential features
  • Increased fat in renal sinus and perinephric tissue
  • Atrophic renal parenchyma
  • Older term was pelvic lipomatosis
Radiology description
  • CT features include marked parenchymal atrophy, abundant adipose tissue in the renal sinus and perirenal regions and calculi
Radiology images

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Ultrasound-renal sinus

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US and CT

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Various images

Case reports
Gross description
  • Abundant adipose tissue in the renal pelvis, usually most pronounced at hilum
  • Associated with renal cortical atrophy, chronic pyelonephritis, renal lithiasis, hydronephrosis
Gross images

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Renal pelvic fat

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Atrophied kidney (fig 4b)

Differential diagnosis
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