Kidney nontumor / medical renal

Tubulointerstitial disease



Last author update: 3 December 2012
Last staff update: 20 September 2023

Copyright: 2002-2023,, Inc.

PubMed Search: Sarcoidosis kidney

Nikhil Sangle, M.D.
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Cite this page: Sangle N. Sarcoidosis. website. Accessed September 26th, 2023.
Definition / general
Case reports
Microscopic (histologic) description
  • Diagnosis of exclusion
  • Interstitial noncaseating granulomatous nephritis, nephrocalcinosis, often segmental thickening and wrinkling of glomerular capillary walls
  • Granulomas look fibrotic with minimal or no lymphocytic cuffing (naked nuclei)
Microscopic (histologic) images

Images hosted on other servers:
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Various images

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Granulomatous interstitial nephritis

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Renal biopsy shows
nonspecific features,
which is common
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Recurrence after renal transplant

Immunofluorescence description
  • No specific findings
Electron microscopy description
  • Numerous single and coalescent calcific microspherules within basement membrane, paramesangial zone and mesangium
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