Kidney nontumor

Tubulointerstitial disease



Topic Completed: 3 December 2012

Minor changes: 17 February 2020

Copyright: 2002-2021,, Inc.

PubMed Search: Sarcoidosis [title] kidney

Nikhil Sangle, M.D.
Page views in 2020: 341
Page views in 2021 to date: 541
Cite this page: Sangle N. Sarcoidosis. website. Accessed December 7th, 2021.
Definition / general
Case reports
Microscopic (histologic) description
  • Diagnosis of exclusion
  • Interstitial noncaseating granulomatous nephritis, nephrocalcinosis, often segmental thickening and wrinkling of glomerular capillary walls
  • Granulomas look fibrotic with minimal or no lymphocytic cuffing (naked nuclei)
Microscopic (histologic) images

Images hosted on other servers:
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Various images

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Granulomatous interstitial nephritis

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Renal biopsy shows
nonspecific features,
which is common
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Recurrence after renal transplant

Immunofluorescence description
  • No specific findings
Electron microscopy description
  • Numerous single and coalescent calcific microspherules within basement membrane, paramesangial zone and mesangium
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