Kidney nontumor / medical renal

Developmental & cystic diseases

Mesothelial cysts

Last author update: 1 December 2011
Last staff update: 23 December 2022 (update in progress)

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PubMed Search: Mesothelial cysts kidney

Mandolin S. Ziadie, M.D.
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Cite this page: Ziadie MS. Mesothelial cysts. website. Accessed March 30th, 2023.
Definition / general
  • Rare; cysts lined by mesothelial cells in vicinity of kidney that may present as renal masses
  • Also called primary retroperitoneal cysts of mesothelial origin
Gross description
  • Thin walled, unilocular cyst filled with clear fluid
  • May be hemorrhagic
Microscopic (histologic) description
  • Thin walled cyst lined by single cell lining of nonpleomorphic cells with abundant eosinophilic cytoplasm, vesicular nuclei and small nucleoli
  • May have small gland-like spaces
Negative stains
Differential diagnosis
  • Lymphangioma: multicystic, has smooth muscle and lymphocytes in cyst wall and lumen, keratin+
  • Mucinous cystadenoma: ovarian-like stroma, mucin+, CEA+, negative for hyaluronic acid
  • Simple hemorrhagic cyst
Additional references
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