Bone marrow neoplastic

Bone marrow - neoplastic myeloid

AML not otherwise specified

AML hypocellular



Last author update: 1 February 2013
Last staff update: 4 February 2022

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PubMed Search: Hypocellular AML


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Cite this page: Mihova D. AML hypocellular. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/leukemiahypocellular.html. Accessed May 19th, 2024.
Definition / general
  • Defined as < 20% bone marrow cellularity, 20% or more are blasts (WHO); other definitions range up to 40% cellularity
  • Up to 10% of AML cases
  • Median age 67 years (Leuk Res 1996;20:563)
  • Rare blasts in peripheral blood
  • Often has smoldering course although intensive chemotherapy may cause complete remission
Case reports
Microscopic (histologic) images

AFIP images
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Markedly hypocellular marrow

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Cells in interstitium are predominantly blasts

Positive stains
Differential diagnosis
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