Bone marrow neoplastic

Bone marrow - plasma cell and lymphoid neoplasms

B lymphoblastic leukemia / lymphoma with recurrent genetic abnormalities

t(5;14)(q31;q32); IGH::IL3

Last author update: 1 February 2013
Last staff update: 28 April 2023

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PubMed Search: B lymphoblastic leukemia IL3-IGH

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Cite this page: Mihova D. t(5;14)(q31;q32); IGH::IL3. website. Accessed June 4th, 2023.
Definition / general
  • Diagnosis based on immunophenotype and genetic findings, even with low blast count
  • Very rare; < 1% of all ALL; both children and adults (Blood 1989;73:2081)
  • Presents with variable eosinophilia; may be asymptomatic and lack any blasts (Medicine (Baltimore) 1990;69:232)
Case reports
Microscopic (histologic) description
  • CD19+ CD10+ lymphoblasts with circulating reactive eosinophils
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