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Sample library

Pan-TRK (EPR17341) IHC IVD assay



Revised: 1 July 2021

Copyright: 2021, PathologyOutlines.com, Inc.

See Also: NTRK stain topic


Definition / general
  • This library contains material that has not been peer reviewed by PathologyOutlines.com
Frequently asked questions

1. What kinds of testing methods can be used to detect NTRK gene fusions? (click for answer)

NTRK gene fusions can be detected using various testing methods, including NGS, immunohistochemistry (IHC), which detects protein expression of both fusion and wild-type; fluorescence in situ hybridization (FISH), and reverse transcriptase polymerase chain reaction (RT-PCR).
Microscopic (histologic) images

Examples of positive control tissues for this
antibody are appendix and cerebellum

Videos

Part 1: biology and testing methods for NTRK fusions

Video descriptions
Part 1: biology and testing methods for NTRK fusions
  • Dr. Denise Croix provides an overview of the function and role pan-TRK IHC plays in testing methodology for NTRK gene fusions
    • NTRK overview
    • Gene fusions
    • Prevalence
    • Methods of detection
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Image 01 Image 02