Other interstitial pneumonitis / fibrosis

Obliterative bronchiolitis

Topic Completed: 1 September 2011

Minor changes: 12 August 2020

Copyright: 2003-2021,, Inc.

PubMed search: obliterative bronchiolitis [title]

Elliot Weisenberg, M.D.
Page views in 2020: 1,225
Page views in 2021 to date: 1,095
Cite this page: Weisenberg E. Obliterative bronchiolitis. website. Accessed September 16th, 2021.
Definition / general
  • Associated with bone marrow, heart and lung transplants, rheumatoid arthritis, penicillamine or gold therapy and post viral infection, especially adenovirus
  • Associated with chronic rejection in lung transplant patients, an irreversible condition with poor prognosis
Microscopic (histologic) description
  • May be patchy, fibrosis in submucosa of bronchioles leading to partial or complete occlusion of small airways
  • Inflammatory cell infiltrates may or may not be present
  • Organizing pneumonia may be present
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