Lung

Infectious

Parasitic

Strongyloides



Topic Completed: 1 September 2011

Minor changes: 31 December 2020

Copyright: 2003-2021, PathologyOutlines.com, Inc.

PubMed search: Strongyloides [title] pulmonary

Elliot Weisenberg, M.D.
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Cite this page: Weisenberg E. Strongyloides. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/lungnontumorstrongyloides.html. Accessed October 25th, 2021.
Clinical features
  • Endemic in Southeastern United States, South America, Southeast Asia and Sub-Saharan Africa
  • Infection occurs when larvae in soil penetrate the skin and travel to the lung via the venous circulation; the worms then travel up the trachea to the oropharynx and are swallowed setting up infection in the small intestine
  • Female worms in the small intestinal mucosa produce eggs asexually (parthenogenesis) that are passed to the soil where they hatch to continue cycle of infection
  • Larvae hatched in the intestines may penetrate the colonic mucosa to travel to the lung to reinitiate infection (autoinfection)
  • Disease usually affects the gastrointestinal tract
  • In immunocompromised patients, severe disease with large burden of parasites may occur; patients may present with alveolar hemorrhage (Prim Care Respir J 2009;18:337)
  • May predispose to invasive infections caused by enteric organisms (Am J Clin Pathol 2007;128:622)
Diagrams / tables

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Life cycle

Life cycle

Microscopic (histologic) description
  • In the lung, eosinphilic pneumonia with hemorrhage may occur
  • Worms may be found in airways, alveoli and blood vessels
Microscopic (histologic) images

Case #133
Small bowel infection

Small bowel infection



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Small bowel infection Small bowel infection

Small bowel infection

Cytology images

Contributed by anonymous
Bronchial wash

Bronchial wash

Pap stain

Pap stain

Diff-Quik

Diff-Quik



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Bronchial wash

Bronchial wash

BAL fluid

BAL fluid

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