Lymph nodes & spleen, nonlymphoma

Lymph nodes-vascular lesions

Angiolipomatous hamartoma



Topic Completed: 1 November 2013

Minor changes: 14 June 2021

Copyright: 2003-2021, PathologyOutlines.com, Inc.

PubMed Search: Angiolipomatous hamartomas


Patricia Tsang, M.D., M.B.A.
Page views in 2020: 1,514
Page views in 2021 to date: 1,494
Cite this page: Tsang P. Angiolipomatous hamartoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/lymphnodesangiolipomatoushyperplasia.html. Accessed October 15th, 2021.
Definition / general
Sites
  • Various nodal sites, including cervical, mediastinal and retroperitoneal lymph nodes
  • Occurs in nodal parenchyma or extracapsular soft tissue
  • Miscellaneous extranodal sites can be involved
Pathophysiology
  • Rare disorder of unknown etiology
  • Pseudotumor; not a true neoplasm
Clinical features
  • Innocuous and slow growing
Radiology images

Images hosted on other servers:

Mesenteric tumor with soft tissue parts

Case reports
Treatment
  • Surgical excision
Gross description
  • Unencapsulated single or multiple yellow and fatty nodules up to 15 cm
  • Tan nodules may represent accompanying hyaline vascular Castleman lymphadenopathy
Gross images

Images hosted on other servers:

Large smooth surfaced mass

Microscopic (histologic) description
  • Noncircumscribed intranodal or extranodal mass
  • Mature adipose tissue and haphazard thick walled muscular vessels of varying sizes
  • No thrombi within disorganized vascular channels
  • Lacks other mesenchymal tissue types, such as muscle
  • No necrosis, dense sclerosis, lipoblasts or marked cytologic atypia
Immunohistochemistry
Differential diagnosis
Back to top
Image 01 Image 02