Lymph nodes & spleen, nonlymphoma

Lymph nodes-vascular lesions

Angiolipomatous hamartoma

Last author update: 1 November 2013
Last staff update: 14 June 2021

Copyright: 2003-2024,, Inc.

PubMed Search: Angiolipomatous hamartomas

Patricia Tsang, M.D., M.B.A.
Page views in 2023: 3,088
Page views in 2024 to date: 459
Cite this page: Tsang P. Angiolipomatous hamartoma. website. Accessed February 23rd, 2024.
Definition / general
  • Various nodal sites, including cervical, mediastinal and retroperitoneal lymph nodes
  • Occurs in nodal parenchyma or extracapsular soft tissue
  • Miscellaneous extranodal sites can be involved
  • Rare disorder of unknown etiology
  • Pseudotumor; not a true neoplasm
Clinical features
  • Innocuous and slow growing
Radiology images

Images hosted on other servers:

Mesenteric tumor with soft tissue parts

Case reports
  • Surgical excision
Gross description
  • Unencapsulated single or multiple yellow and fatty nodules up to 15 cm
  • Tan nodules may represent accompanying hyaline vascular Castleman lymphadenopathy
Gross images

Images hosted on other servers:

Large smooth surfaced mass

Microscopic (histologic) description
  • Noncircumscribed intranodal or extranodal mass
  • Mature adipose tissue and haphazard thick walled muscular vessels of varying sizes
  • No thrombi within disorganized vascular channels
  • Lacks other mesenchymal tissue types, such as muscle
  • No necrosis, dense sclerosis, lipoblasts or marked cytologic atypia
Immunohistochemistry & special stains
Differential diagnosis
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