Lymph nodes & spleen, nonlymphoma
Lymph nodes-inclusions, pigment, ectopic cells or tissue
Asbestos


Topic Completed: 1 February 2014

Minor changes: 1 October 2020

Copyright: 2003-2021, PathologyOutlines.com, Inc.

PubMed Search: Asbestos [title] lymph nodes

Jayalakshmi Balakrishna, M.D.
Abdelsalam Sharabi, M.D.
Page views in 2020: 270
Page views in 2021 to date: 6
Cite this page: Balakrishna J, Sharabi A. Asbestos. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/lymphnodesasbestosbodies.html. Accessed January 23rd, 2021.
Terminology
  • Also called Ferruginous bodies
Epidemiology
  • Usually due to industrial / occupational exposure
Sites
  • Most common in thoracic / hilar lymph nodes
  • Concentration of asbestos fibers in lymph nodes is 2 - 3x higher than in lung
Clinical features
  • Inhaled asbestos fibers have iron protein-mucopolysaccharide coating
  • Enlarged lymph nodes are common
  • Associated symptoms / signs of pulmonary asbestosis
Diagnosis
  • Biopsy of affected lymph node
  • Bleach digestion for confirmation
Radiology description
  • Mediastinal / hilar lymphadenopathy
Prognostic factors
  • Pulmonary asbestosis is a risk factor for lung carcinoma and mesothelioma
Case reports
Clinical images

Images hosted on other servers:

Asbestos with mesothelioma

Enlarged supraclavicular node

Epiphrenic node on right

Node inside lesion

Gross description
  • Lymph nodes may be enlarged but show no significant abnormalities on cut surface
Microscopic (histologic) description
  • Asbestos bodies are golden-brown, beaded, or dumbbell shaped structures with a thin, translucent core
Differential diagnosis
  • Pseudoasbestos bodies
  • Other ferruginous bodies
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