Table of Contents
Definition / general | Case reports | Diagnosis | Microscopic (histologic) description | Differential diagnosisCite this page: DePond WD. Brucellosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/lymphnodesbrucellosis.html. Accessed January 18th, 2021.
Definition / general
- Due to Brucella abortus, melitensis or suis
- Either occupational or food related (milk and cheese)
- Fever, hepatosplenomegaly, rarely lymphadenopathy
Case reports
- 22 year old woman with Kikuchi-Fujimoto necrotizing lymphadenitis associated with brucellosis (Sangre (Barc) 1992;37:201)
- 43 year old man with B. melitensis and subsequent Kikuchi-Fujimoto disease (In Vivo 2003;17:51)
Diagnosis
- Culture, PCR, serology
Microscopic (histologic) description
- Follicular hyperplasia, clusters of epithelioid histiocytes that may form large noncaseating granulomas
- Eosinophils, plasma cells, immunoblasts
Differential diagnosis
