Lymph nodes & spleen, nonlymphoma
Lymph nodes-inclusions, pigment, ectopic cells or tissue

Topic Completed: 1 July 2013

Minor changes: 12 August 2020

Copyright: 2003-2021,, Inc.

PubMed Search: Megakaryocytes [title] lymph nodes

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Cite this page: DePond W. Megakaryocytes. website. Accessed January 25th, 2021.
Definition / general
  • Often associated with extramedullary hematopoiesis when present in lymph nodes
Case reports
Microscopic (histologic) images

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Megakaryocytes in bone marrow

Positive stains
Negative stains
Differential diagnosis
  • Multinucleated histiocytes: larger, more cytoplasm, vesicular nuclei that are not multilobated, CD68+
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