Lymph nodes & spleen, nonlymphoma
Ectopic tissue / inclusions
Salivary gland


Topic Completed: 1 July 2014

Minor changes: 2 November 2020

Copyright: 2003-2021, PathologyOutlines.com, Inc.

PubMed Search: Salivary gland inclusions [title]

Jayalakshmi Balakrishna, M.D.
Abdelsalam Sharabi, M.D.
Page views in 2020: 916
Page views in 2021 to date: 236
Cite this page: Balakrishna J, Sharabi A. Salivary gland. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/lymphnodessalivaryglandinclusions.html. Accessed April 15th, 2021.
Definition / general
  • Benign salivary gland structures in lymph nodes
  • Includes ducts and acini
Terminology
  • Salivary gland inclusions
  • Ectopic salivary tissue
  • Heterotropic salivary gland tissue
Epidemiology
  • Common incidental finding
Sites
  • Most common in upper cervical lymph nodes
  • Rarely - thoracic, mediastinal lymph nodes
Pathophysiology
  • Considered a normal event related to the embryology of the region
Clinical features
  • None - incidental finding
  • Enlarged lymph nodes
Prognostic factors
  • Benign with no significance
  • May undergo diseases of salivary glands including neoplastic processes - Warthin tumor is most common tumor
Case reports
Treatment
  • Usually none, but may be indicated based on clinical situation
Clinical images

Images hosted on other servers:

Circumscribed mass lesions due to
sialometaplasia arising in ectopic
salivary gland ductal inclusions

Gross description
  • Normal / enlarged lymph nodes
Microscopic (histologic) description
  • Both ducts and acini are usually present
  • Benign ducts are lined by double layer of epithelium and myoepithelium
  • Benign acini have zymogen granules
Microscopic (histologic) images

AFIP images
Missing Image

Salivary gland inclusion in lymph node



Images hosted on other servers:

Inclusions undergoing sialometaplasia show extensive squamous metaplasia

Inclusions with sialometaplasia: SMA

Differential diagnosis
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