Pathology Outlines

Lymph nodes & spleen, nonlymphoid

Lymph nodes-inclusions, pigment, ectopic cells or tissue

Silicosis

Topic Completed: 1 July 2013

Minor changes: 3 April 2020

Revised: 1 February 2019, last major update July 2013

Copyright: 2003-2020, PathologyOutlines.com, Inc.

PubMed Search: Silicosis [title] lymph nodes

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Table of Contents

Definition / general | Case reports | Microscopic (histologic) description | Electron microscopy description

Cite this page: DePond W. Silicosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/lymphnodessilicosis.html. Accessed August 11th, 2020.

Definition / general

Exposure to low concentrations of quartz may cause hilar node fibrosis (Occup Environ Med 1998;55:383)

Case reports

Stone splitter presenting with enlarged supraclavicular node (Respirology 1998;3:281)

Microscopic (histologic) description

Sclerohyaline nodule, fibrinoid necrosis, birefringent crystals

Electron microscopy description

Longitudinal splitting and breakage of collagen fibrils, deposition of flocculent electron dense material around collagen fibrils (Hum Pathol 1985;16:393)