Lymph nodes & spleen, nonlymphoma
Lymph nodes-infectious / parasitic disorders
Yersinia pestis


Topic Completed: 1 June 2006

Minor changes: 12 December 2020

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PubMed Search: Yersinia pestis lymph nodes

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Cite this page: DePond WD. Yersinia pestis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/lymphnodesyersiniapestis.html. Accessed January 17th, 2021.
Definition / general
  • Similar to Y. pseudotuberculosis
Clinical features
Diagnosis
  • Gram stain: gram negative, polymorphic, coccoid or ovoid mobile bacteria
  • PCR
  • Cultures
Case reports
Microscopic (histologic) description
  • Capsular thickening and edema
  • Immunoblasts and plasma cells in cortical and paracortical region
  • Large lymphocytes within sinuses, germinal center hyperplasia
  • No granulomas (unlike Y. pseudotuberculosis)
  • Depletion of lymphocytes, edema, necrosis, foamy macrophages
  • Bacteria may involve blood vessels
Positive stains
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