Cite this page: Luca D. Primary cutaneous CD30+. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/lymphomanonBprimarycutT.html. Accessed March 3rd, 2021.
Definition / general
- Primary cutaneous CD30+ lymphoproliferative disorders are the second most common group of the cutaneous T cell lymphomas (CTCL), with 30% of cases (IARC: WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4th Edition, 2008)
- Includes lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large cell lymphoma (C-ALCL)
- Spectrum with overlapping histopathologic and phenotypic features, therefore clinical features are critical for a definitive diagnosis
- Borderline cases exist despite clinicopathologic correlation