Mandible & maxilla

Other benign tumors / tumor-like conditions

Ameloblastic fibroma

Topic Completed: 1 January 2004

Minor changes: 9 November 2020

Copyright: 2004-2021,, Inc.

PubMed Search: Ameloblastic fibroma (mandible OR maxilla)

Nat Pernick, M.D.
Page views in 2020: 3,345
Page views in 2021 to date: 3,664
Cite this page: Pernick N. Ameloblastic fibroma. website. Accessed October 28th, 2021.
Definition / general
  • Rare
  • Usually age 20 or less
  • Benign, rarely recurs
Radiology description
  • Variable radiolucent - radiopaque appearance
  • Simple curettage
Gross description
  • Usually solid
Microscopic (histologic) description
  • Small islands and cords of markedly attenuated ameloblastic epithelium two cells thick within dense collagenous stroma that is often immature
  • Occasional dentin or cementum production and stellate reticulum
  • Also granular cell variant
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Ameloblastic fibroma

Ameloblastic fibroma

Odontogenic islands with cystic change, within immature mesenchymal stroma

AF at scanning magnification

Odontogenic islands

Odontogenic cords within immature mesenchymal stroma

Differential diagnosis
  • Ameloblastoma: no connective tissue stroma, has dentin and enamel
Back to top
Image 01 Image 02