Mandible & maxilla

Benign odontogenic tumors

Ameloblastic fibroma



Last author update: 1 January 2004
Last staff update: 8 August 2022

Copyright: 2004-2022, PathologyOutlines.com, Inc.

PubMed Search: Ameloblastic fibroma


Nat Pernick, M.D.
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Cite this page: Pernick N. Ameloblastic fibroma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/mandiblemaxillaameloblasticfibroma.html. Accessed December 3rd, 2022.
Definition / general
  • Rare
  • Usually age 20 or less
  • Benign, rarely recurs
Radiology description
  • Variable radiolucent - radiopaque appearance
Treatment
  • Simple curettage
Gross description
  • Usually solid
Microscopic (histologic) description
  • Small islands and cords of markedly attenuated ameloblastic epithelium two cells thick within dense collagenous stroma that is often immature
  • Occasional dentin or cementum production and stellate reticulum
  • Also granular cell variant
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.
Ameloblastic fibroma

Ameloblastic fibroma

Odontogenic islands with cystic change, within immature mesenchymal stroma Odontogenic islands with cystic change, within immature mesenchymal stroma Odontogenic islands with cystic change, within immature mesenchymal stroma

Odontogenic islands with cystic change, within immature mesenchymal stroma


AF at scanning magnification

AF at scanning magnification

Odontogenic islands

Odontogenic islands

Odontogenic cords within immature mesenchymal stroma Odontogenic cords within immature mesenchymal stroma

Odontogenic cords within immature mesenchymal stroma

Differential diagnosis
  • Ameloblastoma: no connective tissue stroma, has dentin and enamel
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