Mandible & maxilla

Giant cell lesions & nonepithelial bone cysts


Last author update: 1 October 2013
Last staff update: 10 November 2020

Copyright: 2004-2022,, Inc.

PubMed Search: Cherubism [title]

Nat Pernick, M.D.
Page views in 2021: 1,271
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Cite this page: Pernick N. Cherubism. website. Accessed December 7th, 2022.
Definition / general
  • Hereditary and intraosseous fibrous swellings of jaws
  • Autosomal dominant, bilateral involvement of mandible and maxilla in young individuals
  • Surgery may not be indicated
Microscopic (histologic) description
  • Similar to central giant cell granuloma
  • Also more delicate fibrovascular stroma without bone formation
Microscopic (histologic) images

Contributed by Kelly Magliocca, D.D.S., M.P.H.


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