Mediastinum
Thymic carcinoma
Clear cell
Author: Hanni Gulwani, M.B.B.S.
Last author update: 1 December 2012
Last staff update: 10 June 2020
Copyright: 2003-2023, PathologyOutlines.com, Inc.
PubMed Search: Clear cell thymic carcinoma
Table of Contents
Definition / general | Case reports | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Differential diagnosisCite this page: Gulwani H. Clear cell. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/mediastinumclearcell.html. Accessed June 2nd, 2023.
Definition / general
- Rare; clear cytoplasm due to either glycogen or degenerative changes
- Almost always fatal
Case reports
- 42 year old man (Gen Thorac Cardiovasc Surg 2010;58:98)
Microscopic (histologic) description
- Lobular or occasionally sheet-like growth pattern of polygonal cells with clear cytoplasm, rather bland nuclear features, round vesicular nuclei, prominent nucleoli; delicate fibrovascular stroma (Am J Surg Pathol 1995;19:835)
- No blood lakes, no mucin
Microscopic (histologic) images
Images hosted on other servers:
Large cells with abundant optically clear cytoplasm
Positive stains
Differential diagnosis
