Ectopic hamartomatous thymoma

Topic Completed: 1 December 2012

Minor changes: 15 October 2021

Copyright: 2003-2021,, Inc.

PubMed Search: Ectopic hamartomatous thymoma

Hanni Gulwani, M.B.B.S.
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Cite this page: Gulwani H. Ectopic hamartomatous thymoma. website. Accessed December 6th, 2021.
Definition / general
  • Rare, supraclavicular sternal soft tissue mass
  • Usually adult men
Clinical features
  • May arise from ectopic tissue of third branchial pouch
  • Benign behavior
Case reports
Gross description
  • Well circumscribed, firm, yellow-white, variable microcysts
Microscopic (histologic) description
  • Sheets of spindled epithelial cells resembling neurogenic or fibroblastic tumors
  • Also epithelial nests, thin anastomosing cords and epithelial lined cysts
  • May have focal adipose tissue, small lymphocytes
  • No atypia, no necrosis, no mitotic figures
Microscopic (histologic) images

AFIP images

Spindle cell of mesenchymal-like appearance

Spindle cells

Positive stains
Electron microscopy description
  • Tonofilaments, well developed cell junctions
Differential diagnosis
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