Mediastinum
Other tumors
Metastases
Author: Hanni Gulwani, M.B.B.S.
Last author update: 1 December 2012
Last staff update: 15 August 2022
Copyright: 2003-2023, PathologyOutlines.com, Inc.
PubMed Search: Mediastinum metastatic carcinoma
Table of Contents
Definition / general | Clinical features | Case reports | Microscopic (histologic) images | Stains | Electron microscopy descriptionCite this page: Gulwani H. Metastases. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/mediastinummetastaticcarcinoma.html. Accessed June 2nd, 2023.
Definition / general
- Most mediastinal epithelial neoplasms are metastases, usually from trachea, bronchi, lung, esophagus
- Usually rapidly fatal
Clinical features
- Primary lung tumors may present as huge mediastinal mass with occult bronchial primary
Case reports
- 67 year old man with shortness of breath and huge mediastinal mass (Case of the Week #430)
Microscopic (histologic) images
Stains
- CD5 (suggestive of thymic), PLAP (germ cell), PSA (prostate), S100 (melanoma, others), thyroglobulin (thyroid)
Electron microscopy description
- Premelanosomes suggests melanoma
