Cystic lesions

Pericardial cyst

Last author update: 1 December 2012
Last staff update: 16 August 2022

Copyright: 2003-2023,, Inc.

PubMed Search: Pericardial cyst mediastinum

Hanni Gulwani, M.B.B.S.
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Cite this page: Gulwani H. Pericardial cyst. website. Accessed May 30th, 2023.
Definition / general
  • Usually at right cardiophrenic angle, adherent to pericardium and diaphragm; may communicate with pericardial cavity
  • Due to failure of one of multiple disconnected lacunae to merge with the others
Clinical features
  • Usually asymptomatic patients of all ages anywhere in mediastinum; rarely associated with dyspnea or chest pain
Radiology description
  • Xray: irregular, adjacent to cardiac contour
Case reports
Gross description
  • Thin fibrous wall, unilocular, collapses when opened, smooth cyst lining, serous fluid contents
Microscopic (histologic) description
  • Fibrous tissue lined by bland mesothelium, rarely with papillary hyperplasia, no cholesterol granulomas, no smooth muscle, no cartilage, no specialized epithelium
Microscopic (histologic) images

Images hosted on other servers:

Cyst wall composed of
thin layer of fibrous
tissue lined with single
layer of mesothelial cells

Positive stains
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