Mediastinum
Thymoma
Thymolipoma


Topic Completed: 1 December 2012

Minor changes: 7 February 2020

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Thymolipoma[TI]

Hanni Gulwani, M.B.B.S.
Page views in 2019: 1,221
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Cite this page: Gulwani H. Thymolipoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/mediastinumthymolipoma.html. Accessed August 6th, 2020.
Definition / general
  • Increased thymic volume, due to lobules of mature adipose tissue mixed with unremarkable thymic tissue
  • Benign
  • May be neoplasm of thymic fat (Ann Diagn Pathol 2009;13:185)
Epidemiology
  • Usually young to middle aged adults, found incidentally
Clinical features
  • 10% associated with thymoma-like paraneoplastic symptoms
Case reports
Gross description
  • Encapsulated, up to 20 cm
  • Resembles lipoma
Microscopic (histologic) description
  • Thin fibrous capsule surrounding lobules of mature adipose tissue intimately associated with unremarkable thymic tissue containing cortex, medulla and Hassall corpuscles
  • May have thymic epithelial proliferation, myoid cells, zones of dense fibrosis
Microscopic (histologic) images

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Various images, CK903



Contributed by Snehal Sonawane, M.D.
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Mature adipose tissue admixed with unremarkable thymic tissue

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