Mediastinum
Nonneoplastic
True thymic hyperplasia
Author: Hanni Gulwani, M.B.B.S.
Topic Completed: 1 December 2012
Minor changes: 7 February 2020
Copyright: 2003-2019, PathologyOutlines.com, Inc.
PubMed Search: True thymic hyperplasia
Cite this page: Gulwani H. True thymic hyperplasia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/mediastinumtruethymichyper.html. Accessed March 4th, 2021.
Definition / general
- Thymus larger than normal limits for age, based on tables
- Otherwise histologically unremarkable
Epidemiology
- Often in infants or children or in adults after cancer chemotherapy
Case reports
- 5 week old boy with severe thymic cyst bleeding (Ann Diagn Pathol 2007;11:358)
- 22 year old man with thymic hemorrhage (Pathol Res Pract 2010;206:331)
- 24 year old woman who was treated for T cell lymphoma (J Clin Oncol 2004;22:953)
- 26 year old woman with thymolipoma, suggesting an origin from thymic true hyperplasia (Int J Surg Pathol 2010;18:526)
- 53 year old woman with unilocular thymic cyst (Ann Diagn Pathol 2006;10:32)
Immunohistochemistry
- p63+, XIAP- (Am J Clin Pathol 2009;131:689)
