Nasal cavity, paranasal sinuses, nasopharynx

Benign tumors

Nasal chondromesenchymal hamartoma



Topic Completed: 1 August 2004

Minor changes: 8 October 2020

Copyright: 2004-2021, PathologyOutlines.com, Inc.

PubMed Search: Nasal chondromesenchymal hamartoma

Nat Pernick, M.D.
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Cite this page: Pernick N. Nasal chondromesenchymal hamartoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/nasalchondromes.html. Accessed December 3rd, 2021.
Definition / general
  • Rare; intranasal and paranasal polypoid mass in infants and occasionally older children
  • 2/3 male, mean age 14 months, range 1 day to 7 years
  • Benign but fills nasal cavity and usually extends into ethmoid sinuses
  • May erode bone, including cribriform plate and have an intracranial component
Radiology images

Contributed by I Weng Lao, M.D., Ph.D. and Jian Wang, M.D., Ph.D.

CT scan

Case reports
Treatment
  • Excision
Microscopic (histologic) description
  • Well demarcated mature cartilage, myxoid stroma, focal osteoclast-like giant cells, aneurysmal bone cyst-like formations, spindle cells, collagen fibers
Microscopic (histologic) images

Contributed by I Weng Lao, M.D., Ph.D. and Jian Wang, M.D., Ph.D.

7 month old infant boy



Case #291

Various images

Positive stains
Electron microscopy description
  • Fibroblastic and myofibroblastic differentiation
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