Table of Contents
Definition / general | Microscopic (histologic) description | Positive stains | Negative stains | Differential diagnosis | Additional referencesCite this page: Pernick N. Sinonasal meningioma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/nasalmeningioma.html. Accessed March 26th, 2023.
Definition / general
- Rare, frequently misclassified
- Mean age 48 years, range 13 - 88 years; no gender preference
- Usually primary intranasal or paranasal mass; may also be an intracranial tumor invading sphenoid or frontal sinuses
- Primary extracranial tumors have a good prognosis; intracranial lesions invading into upper respiratory tract are difficult to excise
Microscopic (histologic) description
- Whorled growth pattern of meningothelial spindle cells with psammoma bodies
- May have atypical features
Negative stains
- S100 (usually)
Differential diagnosis
- Angiofibroma
- Cementoossifying fibroma: cellular with fibroblastic stromal cells, calcifications contain cells
- Paraganglioma
- Schwannoma
Additional references