Table of ContentsDefinition / general | Case reports | Microscopic (histologic) description | Microscopic (histologic) images | Board review style question #1 | Board review style answer #1
Cite this page: Pernick N. Invasive fungal sinusitis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/nasalmucor.html. Accessed December 2nd, 2022.
Definition / general
- Relatively common life threatening fungal infection, associated with diabetic ketoacidosis, poor glycemic control or immunosuppression
- Spreads rapidly across nerves and tissue planes to blood vessels of orbit and brain, causes thrombosis, hemorrhage and infarction
- Member of phylum Zygomycota, class Zygomycetes, order Mucorales; found in high organic matter and soil
- Mortality rate of 48%
Microscopic (histologic) description
- Broad nonseptate hyphae branching at 90 degrees, accompanied by numerous neutrophils and histiocytes within granulation tissue
Microscopic (histologic) images
Board review style question #1
Which of the following anatomic sites is most commonly involved in acute invasive fungal sinusitis?
- Nasal septum
- Inferior turbinate
- Ethmoid sinus
- Middle turbinate