Oral cavity & oropharynx
Other nonneoplastic
Ephelis
Author: Charu Thakral, M.D.
Last author update: 1 April 2013
Last staff update: 22 August 2022
Copyright: 2002-2024, PathologyOutlines.com, Inc.
PubMed Search: Ephelis oral cavity
Table of Contents
Definition / general | Case reports | Clinical images | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosisCite this page: Thakral C. Ephelis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/oralcavityephelis.html. Accessed April 25th, 2024.
Definition / general
- Also called freckle
- Solitary melanotic macules, usually of lower lip
- More common in women; associated with Peutz-Jeghers syndrome
Case reports
- 4 patients with labial melanotic macule (Dermatology 2012;224:209)
Clinical images
Images hosted on other servers:
55 year old woman
60 year old man
26 year old woman
37 year old woman
Microscopic (histologic) description
- Hyperpigmentation of basal layer with elongation of rete ridges
Microscopic (histologic) images
Images hosted on other servers:
Keratinocytes (fig d)
Differential diagnosis
- Melanoacanthoma:
- Melanocytes mixed with keratinocytes
- Melanosis:
- Pigmented patches in hard palate or gingiva
