Oral cavity & oropharynx


Grossing & features to report

Topic Completed: 1 November 2013

Minor changes: 17 February 2020

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PubMed Search: Features to report oral cavity[TI]

Nat Pernick, M.D.
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Cite this page: Pernick N Grossing & features to report. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/oralcavityfeaturestoreport.html. Accessed December 8th, 2021.
  • At least one section per 1 cm of tumor for large tumors, including tumor center and periphery
  • Submit entire tumor if can do so in 5 sections or less
  • Resection margins
  • Save intervening levels on biopsies for special stains
Features to Report
  • Tumor histologic type and pattern
  • Tumor size and location
  • Tumor histologic grade
  • Depth of invasion (not used for TNM staging)
  • Pattern of invasion (noncohesive irregular cords, infiltrative single cells, well defined blunt pushing borders, thick rounded invasive cords)
  • Tumor extension to adjacent structures
  • Status of resection margins
  • Vascular invasion
  • Perineural invasion
  • Lymph nodes: for each level, number obtained, number involved by tumor, size of nodal metastases and presence of extracapsular spread
  • Dysplasia
  • References: Mod Pathol 2000;13:1038

  • Endophytic tumors: measure perpendicularly from surface of invasive carcinoma to deepest area of involvement, using nontangential sections with a clearly recognizable surface component
  • Exophytic tumors: measure tumor thickness from surface to deepest area
  • Ulcerated tumors: measure from ulcer base to deepest area as well as from surface of most lateral extent of invasive carcinoma to deepest area
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