Oral cavity & oropharynx

Inflammatory / immune mediated (noninfectious)

Granulomatous inflammation

Topic Completed: 1 February 2013

Minor changes: 12 October 2020

Copyright: 2002-2021, PathologyOutlines.com, Inc.

PubMed Search: Granulomatous inflammation oral cavity

Charu Thakral, M.D.
Page views in 2020: 1,298
Page views in 2021 to date: 1,610
Cite this page: Thakral C. Granulomatous inflammation. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/oralcavitygranulomatousinflamm.html. Accessed December 6th, 2021.
Definition / general
  • Associated with chronic recurrent tonsillitis
  • Usually benign course, no specific organism recovered
  • Must rule out infectious causes (tuberculosis, tertiary syphilis, salmonella, mycotic granulomas), systemic causes (sarcoidosis, Crohn's, Granulomatosis with polyangiitis (Wegener's), eosinophilic granuloma), foreign body reaction, cholesterol granuloma
  • Idiopathic orofacial granulomatosis: condition restricted to oral and maxillofacial region without any identifiable systemic granulomatous disease
Case reports
  • Individualized and often needs to change for each patient; includes corticosteroids or other drugs, gingivectomy
Clinical images

Images hosted on other servers:

9 year old girl:


1 year follow up

11 year old boy:



Microscopic (histologic) images

Images hosted on other servers:

Multiple granulomas

Lip and gingival biopsies

Granulomatous lesion and infiltrates

Back to top
Image 01 Image 02