Oral cavity & oropharynx

Inflammatory / immune mediated (noninfectious)

Inflammatory papillary hyperplasia

Topic Completed: 1 March 2013

Minor changes: 12 October 2020

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PubMed Search: Papillary hyperplasia[TIAB] oral cavity

Charu Thakral, M.D.
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Cite this page: Thakral C. Inflammatory papillary hyperplasia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/oralcavitypapillaryhyperplasia.html. Accessed December 8th, 2021.
Definition / general
  • Common, usually involves palate or lingual mandibular gingiva
  • Called palatal papillomatosis in palate
  • Middle aged and older persons, 2/3 female
  • Associated with ill fitting dentures or partial dentures (Braz Dent J 2009;20:243), wearing prostheses at night, poor oral hygiene; also candidiasis
  • Not a premalignant condition
  • Removal of offending agent; proper fitting dentures
  • Complete excision
Clinical images

Images hosted on other servers:

Multiple small nodules on palate

Gross description
  • Multiple red polyp-like projections, often under ill fitting dentures and usually in palate
Microscopic (histologic) description
  • Exophytic mucosal epithelial hyperplasia, including pseudoepitheliomatous hyperplasia and submucosal fibrous hyperplasia
  • Islands of hyperplastic squamous mucosa may appear in submucosa
  • May have chronic inflammation of accessory salivary glands; no dysplasia
Microscopic (histologic) images

Images hosted on other servers:

Inflamed bulbous projection

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