Oral cavity & oropharynx

Inflammatory / immune mediated (noninfectious)

Traumatic ulceration with stroma eosinophilia (TUGSE)



Topic Completed: 1 March 2013

Minor changes: 4 August 2021

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PubMed Search: Traumatic ulceration with stroma eosinophilia

Charu Thakral, M.D.
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Cite this page: Thakral C. Traumatic ulceration with stroma eosinophilia (TUGSE). PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/oralcavitytongueeosinophilia.html. Accessed December 8th, 2021.
Definition / general
  • Resembles carcinoma clinically
  • Presumed due to crush injury of tongue muscle
Terminology
  • Also called ulcerative eosinophilic granuloma, Riga-Fede disease, traumatic granuloma
Case reports
Clinical images

Images hosted on other servers:

70 year old woman:

Painful ulcer of tongue

Ill fitting prosthesis

Healing after removal of prosthesis


6 month old boy:

Ulcerative swelling

Microscopic (histologic) description
  • Eosinophils and other inflammatory cells in submucosa, mucosa, salivary glands
  • Dilated vessels often present
Microscopic (histologic) images

Images hosted on other servers:

Mixed cellular infiltrate

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