Oral cavity & oropharynx

Potentially malignant & dysplasia

Verrucous hyperplasia / proliferative verrucous leukoplakia

Last author update: 1 November 2013
Last staff update: 13 October 2020

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PubMed Search: Verrucous hyperplasia oral cavity

Nat Pernick, M.D.
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Cite this page: Pernick N. Verrucous hyperplasia / proliferative verrucous leukoplakia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/oralcavityverrucoushyperplasia.html. Accessed August 15th, 2022.
Definition / general
  • Slow growing, persistent and often multifocal
  • May represent precursor lesion to verrucous carcinoma, dysplasia or other carcinomas
  • 29% of cases are associated with verrucous carcinoma
Microscopic (histologic) description
  • Mature, hyperkeratotic proliferation and entirely exophytic with no downward proliferation of rete pegs
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