Endometrioid tumors

Endometrioid cystadenoma / adenofibroma

Topic Completed: 1 December 2012

Minor changes: 19 October 2020

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PubMed Search: Ovarian endometrioid adenofibroma

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Cite this page: Ehdaivand S. Endometrioid cystadenoma / adenofibroma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/ovarytumorendometadenofibroma.html. Accessed October 20th, 2021.
Definition / general
Gross images

AFIP images

Mostly fibromatous, small and medium sized cysts

With endometriosis

Microscopic (histologic) description
  • Cystadenoma:
    • Cystic tumor with endometroid features
    • May have squamous morules, ciliated or mucinous features
    • No cytologic atypia, no architectural complexity
    • Benign lesions may be adenofibroma, adenoma or cystadenoma
  • Adenofibroma:
    • Endometroid and fibroma-like features; may have occasional mitotic figures
    • There should be no cytologic or architectural atypia
Microscopic (histologic) images

AFIP images

Irregularly shaped glands and fibromatous stroma

With squamous differentiation

Differential diagnosis
  • Endometriosis: will have endometrial stroma
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